Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance.
Identifieur interne : 000768 ( Main/Exploration ); précédent : 000767; suivant : 000769Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance.
Auteurs : Ashley P L. Marsh [Australie] ; Delphine Heron [France] ; Timothy J. Edwards [Australie] ; Angélique Quartier [France] ; Charles Galea [Australie] ; Caroline Nava [France] ; Agnès Rastetter [France] ; Marie-Laure Moutard [France] ; Vicki Anderson [Australie] ; Pierre Bitoun [France] ; Jens Bunt [Australie] ; Anne Faudet [France] ; Catherine Garel [France] ; Greta Gillies [Australie] ; Ilan Gobius [Australie] ; Justine Guegan [France] ; Solveig Heide [France] ; Boris Keren [France] ; Fabien Lesne [France] ; Vesna Lukic [Australie] ; Simone A. Mandelstam [Australie] ; George Mcgillivray [Australie] ; Alissandra Mcilroy [Australie] ; Aurélie Méneret [France] ; Cyril Mignot [France] ; Laura R. Morcom [Australie] ; Sylvie Odent [France] ; Annalisa Paolino [Australie] ; Kate Pope [Australie] ; Florence Riant [France] ; Gail A. Robinson [Australie] ; Megan Spencer-Smith [Australie] ; Myriam Srour [Canada] ; Sarah E M. Stephenson [Australie] ; Rick Tankard [Australie] ; Oriane Trouillard [France] ; Quentin Welniarz [France] ; Amanda Wood [Australie] ; Alexis Brice [France] ; Guy Rouleau [Canada] ; Tania Attié-Bitach [France] ; Martin B. Delatycki [Australie] ; Jean-Louis Mandel [France] ; David J. Amor [Australie] ; Emmanuel Roze [France] ; Amélie Piton [France] ; Melanie Bahlo [Australie] ; Thierry Billette De Villemeur [France] ; Elliott H. Sherr [États-Unis] ; Richard J. Leventer [Australie] ; Linda J. Richards [Australie] ; Paul J. Lockhart [Australie] ; Christel Depienne [France]Source :
- Nature genetics [ 1546-1718 ] ; 2017.
Descripteurs français
- KwdFr :
- Agénésie du corps calleux (génétique), Cellules souches neurales (anatomopathologie), Corps calleux (anatomopathologie), Encéphale (anatomopathologie), Famille, Femelle, Humains, Incapacités de développement (génétique), Malformations du système nerveux (génétique), Malformations multiples (génétique), Mutation (génétique), Mâle, Phénotype, Protéines suppresseurs de tumeurs (génétique), Pénétrance, Récepteurs de surface cellulaire (génétique).
- MESH :
- anatomopathologie : Cellules souches neurales, Corps calleux, Encéphale.
- génétique : Agénésie du corps calleux, Incapacités de développement, Malformations du système nerveux, Malformations multiples, Mutation, Protéines suppresseurs de tumeurs, Récepteurs de surface cellulaire.
- Famille, Femelle, Humains, Mâle, Phénotype, Pénétrance.
English descriptors
- KwdEn :
- Abnormalities, Multiple (genetics), Agenesis of Corpus Callosum (genetics), Brain (pathology), Corpus Callosum (pathology), Developmental Disabilities (genetics), Family, Female, Humans, Male, Mutation (genetics), Nervous System Malformations (genetics), Neural Stem Cells (pathology), Penetrance, Phenotype, Receptors, Cell Surface (genetics), Tumor Suppressor Proteins (genetics).
- MESH :
- chemical , genetics : Receptors, Cell Surface, Tumor Suppressor Proteins.
- genetics : Abnormalities, Multiple, Agenesis of Corpus Callosum, Developmental Disabilities, Mutation, Nervous System Malformations.
- pathology : Brain, Corpus Callosum, Neural Stem Cells.
- Family, Female, Humans, Male, Penetrance, Phenotype.
Abstract
Brain malformations involving the corpus callosum are common in children with developmental disabilities. We identified DCC mutations in four families and five sporadic individuals with isolated agenesis of the corpus callosum (ACC) without intellectual disability. DCC mutations result in variable dominant phenotypes with decreased penetrance, including mirror movements and ACC associated with a favorable developmental prognosis. Possible phenotypic modifiers include the type and location of mutation and the sex of the individual.
DOI: 10.1038/ng.3794
PubMed: 28250454
Affiliations:
- Australie, Canada, France, États-Unis
- Alsace (région administrative), Californie, Grand Est, Québec, Région Bretagne, Victoria (État), Île-de-France
- Melbourne, Montréal, Paris, Rennes, Strasbourg
- Université McGill, Université de Melbourne, Université de Strasbourg
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000D83
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- to stream PubMed, to step Checkpoint: 000D80
- to stream Ncbi, to step Merge: 004390
- to stream Ncbi, to step Curation: 004390
- to stream Ncbi, to step Checkpoint: 004390
- to stream Main, to step Merge: 000763
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Le document en format XML
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xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lesne, Fabien" sort="Lesne, Fabien" uniqKey="Lesne F" first="Fabien" last="Lesne">Fabien Lesne</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lukic, Vesna" sort="Lukic, Vesna" uniqKey="Lukic V" first="Vesna" last="Lukic">Vesna Lukic</name><affiliation wicri:level="1"><nlm:affiliation>Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Mandelstam, Simone A" sort="Mandelstam, Simone A" uniqKey="Mandelstam S" first="Simone A" last="Mandelstam">Simone A. Mandelstam</name><affiliation wicri:level="4"><nlm:affiliation>Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Paediatrics, University of Melbourne, Parkville, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Mcgillivray, George" sort="Mcgillivray, George" uniqKey="Mcgillivray G" first="George" last="Mcgillivray">George Mcgillivray</name><affiliation wicri:level="1"><nlm:affiliation>Victorian Clinical Genetics Services, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Victorian Clinical Genetics Services, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Mcilroy, Alissandra" sort="Mcilroy, Alissandra" uniqKey="Mcilroy A" first="Alissandra" last="Mcilroy">Alissandra Mcilroy</name><affiliation wicri:level="1"><nlm:affiliation>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Meneret, Aurelie" sort="Meneret, Aurelie" uniqKey="Meneret A" first="Aurélie" last="Méneret">Aurélie Méneret</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mignot, Cyril" sort="Mignot, Cyril" uniqKey="Mignot C" first="Cyril" last="Mignot">Cyril Mignot</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Morcom, Laura R" sort="Morcom, Laura R" uniqKey="Morcom L" first="Laura R" last="Morcom">Laura R. Morcom</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Odent, Sylvie" sort="Odent, Sylvie" uniqKey="Odent S" first="Sylvie" last="Odent">Sylvie Odent</name><affiliation wicri:level="3"><nlm:affiliation>Service de Génétique Clinique, Centre de Référence CLAD-Ouest, CHU Rennes, Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service de Génétique Clinique, Centre de Référence CLAD-Ouest, CHU Rennes, Rennes</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Paolino, Annalisa" sort="Paolino, Annalisa" uniqKey="Paolino A" first="Annalisa" last="Paolino">Annalisa Paolino</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Pope, Kate" sort="Pope, Kate" uniqKey="Pope K" first="Kate" last="Pope">Kate Pope</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Riant, Florence" sort="Riant, Florence" uniqKey="Riant F" first="Florence" last="Riant">Florence Riant</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Groupe Hospitalier Saint-Louis -La Riboisière -Fernand Vidal, Laboratoire de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Groupe Hospitalier Saint-Louis -La Riboisière -Fernand Vidal, Laboratoire de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Robinson, Gail A" sort="Robinson, Gail A" uniqKey="Robinson G" first="Gail A" last="Robinson">Gail A. Robinson</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychology Research Unit, School of Psychology, University of Queensland, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychology Research Unit, School of Psychology, University of Queensland, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Spencer Smith, Megan" sort="Spencer Smith, Megan" uniqKey="Spencer Smith M" first="Megan" last="Spencer-Smith">Megan Spencer-Smith</name><affiliation wicri:level="1"><nlm:affiliation>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Srour, Myriam" sort="Srour, Myriam" uniqKey="Srour M" first="Myriam" last="Srour">Myriam Srour</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, Quebec</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Stephenson, Sarah E M" sort="Stephenson, Sarah E M" uniqKey="Stephenson S" first="Sarah E M" last="Stephenson">Sarah E M. Stephenson</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Tankard, Rick" sort="Tankard, Rick" uniqKey="Tankard R" first="Rick" last="Tankard">Rick Tankard</name><affiliation wicri:level="1"><nlm:affiliation>Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Trouillard, Oriane" sort="Trouillard, Oriane" uniqKey="Trouillard O" first="Oriane" last="Trouillard">Oriane Trouillard</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Welniarz, Quentin" sort="Welniarz, Quentin" uniqKey="Welniarz Q" first="Quentin" last="Welniarz">Quentin Welniarz</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Wood, Amanda" sort="Wood, Amanda" uniqKey="Wood A" first="Amanda" last="Wood">Amanda Wood</name><affiliation wicri:level="1"><nlm:affiliation>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Brice, Alexis" sort="Brice, Alexis" uniqKey="Brice A" first="Alexis" last="Brice">Alexis Brice</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Rouleau, Guy" sort="Rouleau, Guy" uniqKey="Rouleau G" first="Guy" last="Rouleau">Guy Rouleau</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Neurosurgery, McGill University Health Center, Montreal, Quebec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Neurology and Neurosurgery, McGill University Health Center, Montreal, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Attie Bitach, Tania" sort="Attie Bitach, Tania" uniqKey="Attie Bitach T" first="Tania" last="Attié-Bitach">Tania Attié-Bitach</name><affiliation wicri:level="3"><nlm:affiliation>INSERM U1163, Laboratory of Embryology and Genetics of Congenital Malformations, Paris-Descartes University, Sorbonne Paris Cité and Imagine Institute, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1163, Laboratory of Embryology and Genetics of Congenital Malformations, Paris-Descartes University, Sorbonne Paris Cité and Imagine Institute, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Delatycki, Martin B" sort="Delatycki, Martin B" uniqKey="Delatycki M" first="Martin B" last="Delatycki">Martin B. Delatycki</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Mandel, Jean Louis" sort="Mandel, Jean Louis" uniqKey="Mandel J" first="Jean-Louis" last="Mandel">Jean-Louis Mandel</name><affiliation wicri:level="4"><nlm:affiliation>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement><settlement type="city">Strasbourg</settlement></placeName><orgName type="university">Université de Strasbourg</orgName></affiliation></author><author><name sortKey="Amor, David J" sort="Amor, David J" uniqKey="Amor D" first="David J" last="Amor">David J. Amor</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Piton, Amelie" sort="Piton, Amelie" uniqKey="Piton A" first="Amélie" last="Piton">Amélie Piton</name><affiliation wicri:level="4"><nlm:affiliation>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement><settlement type="city">Strasbourg</settlement></placeName><orgName type="university">Université de Strasbourg</orgName></affiliation></author><author><name sortKey="Bahlo, Melanie" sort="Bahlo, Melanie" uniqKey="Bahlo M" first="Melanie" last="Bahlo">Melanie Bahlo</name><affiliation wicri:level="1"><nlm:affiliation>Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Billette De Villemeur, Thierry" sort="Billette De Villemeur, Thierry" uniqKey="Billette De Villemeur T" first="Thierry" last="Billette De Villemeur">Thierry Billette De Villemeur</name><affiliation wicri:level="3"><nlm:affiliation>Centre de Référence `Déficiences Intellectuelles de Causes Rares', Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre de Référence `Déficiences Intellectuelles de Causes Rares', Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Sherr, Elliott H" sort="Sherr, Elliott H" uniqKey="Sherr E" first="Elliott H" last="Sherr">Elliott H. Sherr</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, UCSF Benioff Children's Hospital, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, UCSF Benioff Children's Hospital, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Leventer, Richard J" sort="Leventer, Richard J" uniqKey="Leventer R" first="Richard J" last="Leventer">Richard J. Leventer</name><affiliation wicri:level="4"><nlm:affiliation>Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Paediatrics, University of Melbourne, Parkville, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Richards, Linda J" sort="Richards, Linda J" uniqKey="Richards L" first="Linda J" last="Richards">Linda J. Richards</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Lockhart, Paul J" sort="Lockhart, Paul J" uniqKey="Lockhart P" first="Paul J" last="Lockhart">Paul J. Lockhart</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Depienne, Christel" sort="Depienne, Christel" uniqKey="Depienne C" first="Christel" last="Depienne">Christel Depienne</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28250454</idno><idno type="pmid">28250454</idno><idno type="doi">10.1038/ng.3794</idno><idno type="wicri:Area/PubMed/Corpus">000D83</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D83</idno><idno type="wicri:Area/PubMed/Curation">000D80</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000D80</idno><idno type="wicri:Area/PubMed/Checkpoint">000D80</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000D80</idno><idno type="wicri:Area/Ncbi/Merge">004390</idno><idno type="wicri:Area/Ncbi/Curation">004390</idno><idno type="wicri:Area/Ncbi/Checkpoint">004390</idno><idno type="wicri:Area/Main/Merge">000763</idno><idno type="wicri:Area/Main/Curation">000768</idno><idno type="wicri:Area/Main/Exploration">000768</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance.</title><author><name sortKey="Marsh, Ashley P L" sort="Marsh, Ashley P L" uniqKey="Marsh A" first="Ashley P L" last="Marsh">Ashley P L. Marsh</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Heron, Delphine" sort="Heron, Delphine" uniqKey="Heron D" first="Delphine" last="Heron">Delphine Heron</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Edwards, Timothy J" sort="Edwards, Timothy J" uniqKey="Edwards T" first="Timothy J" last="Edwards">Timothy J. Edwards</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Quartier, Angelique" sort="Quartier, Angelique" uniqKey="Quartier A" first="Angélique" last="Quartier">Angélique Quartier</name><affiliation wicri:level="4"><nlm:affiliation>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement><settlement type="city">Strasbourg</settlement></placeName><orgName type="university">Université de Strasbourg</orgName></affiliation></author><author><name sortKey="Galea, Charles" sort="Galea, Charles" uniqKey="Galea C" first="Charles" last="Galea">Charles Galea</name><affiliation wicri:level="1"><nlm:affiliation>Drug Delivery, Disposition and Dynamics (D4), Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Drug Delivery, Disposition and Dynamics (D4), Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Nava, Caroline" sort="Nava, Caroline" uniqKey="Nava C" first="Caroline" last="Nava">Caroline Nava</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Rastetter, Agnes" sort="Rastetter, Agnes" uniqKey="Rastetter A" first="Agnès" last="Rastetter">Agnès Rastetter</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Moutard, Marie Laure" sort="Moutard, Marie Laure" uniqKey="Moutard M" first="Marie-Laure" last="Moutard">Marie-Laure Moutard</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital Trousseau, Service de Neuropédiatrie, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital Trousseau, Service de Neuropédiatrie, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Anderson, Vicki" sort="Anderson, Vicki" uniqKey="Anderson V" first="Vicki" last="Anderson">Vicki Anderson</name><affiliation wicri:level="1"><nlm:affiliation>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Bitoun, Pierre" sort="Bitoun, Pierre" uniqKey="Bitoun P" first="Pierre" last="Bitoun">Pierre Bitoun</name><affiliation wicri:level="1"><nlm:affiliation>Génétique Médicale, CHU Paris Nord, Hôpital Jean Verdier, Bondy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Génétique Médicale, CHU Paris Nord, Hôpital Jean Verdier, Bondy</wicri:regionArea><wicri:noRegion>Bondy</wicri:noRegion><wicri:noRegion>Bondy</wicri:noRegion></affiliation></author><author><name sortKey="Bunt, Jens" sort="Bunt, Jens" uniqKey="Bunt J" first="Jens" last="Bunt">Jens Bunt</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Faudet, Anne" sort="Faudet, Anne" uniqKey="Faudet A" first="Anne" last="Faudet">Anne Faudet</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Garel, Catherine" sort="Garel, Catherine" uniqKey="Garel C" first="Catherine" last="Garel">Catherine Garel</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP GHUEP, Hôpital Armand Trousseau, Service de Radiologie, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP GHUEP, Hôpital Armand Trousseau, Service de Radiologie, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Gillies, Greta" sort="Gillies, Greta" uniqKey="Gillies G" first="Greta" last="Gillies">Greta Gillies</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Gobius, Ilan" sort="Gobius, Ilan" uniqKey="Gobius I" first="Ilan" last="Gobius">Ilan Gobius</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Guegan, Justine" sort="Guegan, Justine" uniqKey="Guegan J" first="Justine" last="Guegan">Justine Guegan</name><affiliation wicri:level="3"><nlm:affiliation>iCONICS Facility, ICM, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>iCONICS Facility, ICM, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Heide, Solveig" sort="Heide, Solveig" uniqKey="Heide S" first="Solveig" last="Heide">Solveig Heide</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Keren, Boris" sort="Keren, Boris" uniqKey="Keren B" first="Boris" last="Keren">Boris Keren</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lesne, Fabien" sort="Lesne, Fabien" uniqKey="Lesne F" first="Fabien" last="Lesne">Fabien Lesne</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lukic, Vesna" sort="Lukic, Vesna" uniqKey="Lukic V" first="Vesna" last="Lukic">Vesna Lukic</name><affiliation wicri:level="1"><nlm:affiliation>Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Mandelstam, Simone A" sort="Mandelstam, Simone A" uniqKey="Mandelstam S" first="Simone A" last="Mandelstam">Simone A. Mandelstam</name><affiliation wicri:level="4"><nlm:affiliation>Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Paediatrics, University of Melbourne, Parkville, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Mcgillivray, George" sort="Mcgillivray, George" uniqKey="Mcgillivray G" first="George" last="Mcgillivray">George Mcgillivray</name><affiliation wicri:level="1"><nlm:affiliation>Victorian Clinical Genetics Services, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Victorian Clinical Genetics Services, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Mcilroy, Alissandra" sort="Mcilroy, Alissandra" uniqKey="Mcilroy A" first="Alissandra" last="Mcilroy">Alissandra Mcilroy</name><affiliation wicri:level="1"><nlm:affiliation>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Meneret, Aurelie" sort="Meneret, Aurelie" uniqKey="Meneret A" first="Aurélie" last="Méneret">Aurélie Méneret</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mignot, Cyril" sort="Mignot, Cyril" uniqKey="Mignot C" first="Cyril" last="Mignot">Cyril Mignot</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Morcom, Laura R" sort="Morcom, Laura R" uniqKey="Morcom L" first="Laura R" last="Morcom">Laura R. Morcom</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Odent, Sylvie" sort="Odent, Sylvie" uniqKey="Odent S" first="Sylvie" last="Odent">Sylvie Odent</name><affiliation wicri:level="3"><nlm:affiliation>Service de Génétique Clinique, Centre de Référence CLAD-Ouest, CHU Rennes, Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service de Génétique Clinique, Centre de Référence CLAD-Ouest, CHU Rennes, Rennes</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Paolino, Annalisa" sort="Paolino, Annalisa" uniqKey="Paolino A" first="Annalisa" last="Paolino">Annalisa Paolino</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Pope, Kate" sort="Pope, Kate" uniqKey="Pope K" first="Kate" last="Pope">Kate Pope</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Riant, Florence" sort="Riant, Florence" uniqKey="Riant F" first="Florence" last="Riant">Florence Riant</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Groupe Hospitalier Saint-Louis -La Riboisière -Fernand Vidal, Laboratoire de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Groupe Hospitalier Saint-Louis -La Riboisière -Fernand Vidal, Laboratoire de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Robinson, Gail A" sort="Robinson, Gail A" uniqKey="Robinson G" first="Gail A" last="Robinson">Gail A. Robinson</name><affiliation wicri:level="1"><nlm:affiliation>Neuropsychology Research Unit, School of Psychology, University of Queensland, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neuropsychology Research Unit, School of Psychology, University of Queensland, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Spencer Smith, Megan" sort="Spencer Smith, Megan" uniqKey="Spencer Smith M" first="Megan" last="Spencer-Smith">Megan Spencer-Smith</name><affiliation wicri:level="1"><nlm:affiliation>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Srour, Myriam" sort="Srour, Myriam" uniqKey="Srour M" first="Myriam" last="Srour">Myriam Srour</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, Quebec</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Stephenson, Sarah E M" sort="Stephenson, Sarah E M" uniqKey="Stephenson S" first="Sarah E M" last="Stephenson">Sarah E M. Stephenson</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Tankard, Rick" sort="Tankard, Rick" uniqKey="Tankard R" first="Rick" last="Tankard">Rick Tankard</name><affiliation wicri:level="1"><nlm:affiliation>Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Trouillard, Oriane" sort="Trouillard, Oriane" uniqKey="Trouillard O" first="Oriane" last="Trouillard">Oriane Trouillard</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Welniarz, Quentin" sort="Welniarz, Quentin" uniqKey="Welniarz Q" first="Quentin" last="Welniarz">Quentin Welniarz</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Wood, Amanda" sort="Wood, Amanda" uniqKey="Wood A" first="Amanda" last="Wood">Amanda Wood</name><affiliation wicri:level="1"><nlm:affiliation>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Imaging and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Brice, Alexis" sort="Brice, Alexis" uniqKey="Brice A" first="Alexis" last="Brice">Alexis Brice</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Rouleau, Guy" sort="Rouleau, Guy" uniqKey="Rouleau G" first="Guy" last="Rouleau">Guy Rouleau</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Neurosurgery, McGill University Health Center, Montreal, Quebec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Neurology and Neurosurgery, McGill University Health Center, Montreal, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Attie Bitach, Tania" sort="Attie Bitach, Tania" uniqKey="Attie Bitach T" first="Tania" last="Attié-Bitach">Tania Attié-Bitach</name><affiliation wicri:level="3"><nlm:affiliation>INSERM U1163, Laboratory of Embryology and Genetics of Congenital Malformations, Paris-Descartes University, Sorbonne Paris Cité and Imagine Institute, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM U1163, Laboratory of Embryology and Genetics of Congenital Malformations, Paris-Descartes University, Sorbonne Paris Cité and Imagine Institute, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Delatycki, Martin B" sort="Delatycki, Martin B" uniqKey="Delatycki M" first="Martin B" last="Delatycki">Martin B. Delatycki</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Mandel, Jean Louis" sort="Mandel, Jean Louis" uniqKey="Mandel J" first="Jean-Louis" last="Mandel">Jean-Louis Mandel</name><affiliation wicri:level="4"><nlm:affiliation>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement><settlement type="city">Strasbourg</settlement></placeName><orgName type="university">Université de Strasbourg</orgName></affiliation></author><author><name sortKey="Amor, David J" sort="Amor, David J" uniqKey="Amor D" first="David J" last="Amor">David J. Amor</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle Épinière (ICM), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Piton, Amelie" sort="Piton, Amelie" uniqKey="Piton A" first="Amélie" last="Piton">Amélie Piton</name><affiliation wicri:level="4"><nlm:affiliation>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IGBMC, Université de Strasbourg, CNRS, INSERM, UMR7104 U964, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement><settlement type="city">Strasbourg</settlement></placeName><orgName type="university">Université de Strasbourg</orgName></affiliation></author><author><name sortKey="Bahlo, Melanie" sort="Bahlo, Melanie" uniqKey="Bahlo M" first="Melanie" last="Bahlo">Melanie Bahlo</name><affiliation wicri:level="1"><nlm:affiliation>Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Billette De Villemeur, Thierry" sort="Billette De Villemeur, Thierry" uniqKey="Billette De Villemeur T" first="Thierry" last="Billette De Villemeur">Thierry Billette De Villemeur</name><affiliation wicri:level="3"><nlm:affiliation>Centre de Référence `Déficiences Intellectuelles de Causes Rares', Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre de Référence `Déficiences Intellectuelles de Causes Rares', Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Sherr, Elliott H" sort="Sherr, Elliott H" uniqKey="Sherr E" first="Elliott H" last="Sherr">Elliott H. Sherr</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, UCSF Benioff Children's Hospital, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, UCSF Benioff Children's Hospital, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Leventer, Richard J" sort="Leventer, Richard J" uniqKey="Leventer R" first="Richard J" last="Leventer">Richard J. Leventer</name><affiliation wicri:level="4"><nlm:affiliation>Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Paediatrics, University of Melbourne, Parkville, Victoria</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Richards, Linda J" sort="Richards, Linda J" uniqKey="Richards L" first="Linda J" last="Richards">Linda J. Richards</name><affiliation wicri:level="1"><nlm:affiliation>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Queensland Brain Institute, University of Queensland, St. Lucia, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Lockhart, Paul J" sort="Lockhart, Paul J" uniqKey="Lockhart P" first="Paul J" last="Lockhart">Paul J. Lockhart</name><affiliation wicri:level="1"><nlm:affiliation>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Depienne, Christel" sort="Depienne, Christel" uniqKey="Depienne C" first="Christel" last="Depienne">Christel Depienne</name><affiliation wicri:level="3"><nlm:affiliation>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>AP-HP, Hôpital de la Pitié-Salpêtrière, Département de Génétique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="eISSN">1546-1718</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Abnormalities, Multiple (genetics)</term><term>Agenesis of Corpus Callosum (genetics)</term><term>Brain (pathology)</term><term>Corpus Callosum (pathology)</term><term>Developmental Disabilities (genetics)</term><term>Family</term><term>Female</term><term>Humans</term><term>Male</term><term>Mutation (genetics)</term><term>Nervous System Malformations (genetics)</term><term>Neural Stem Cells (pathology)</term><term>Penetrance</term><term>Phenotype</term><term>Receptors, Cell Surface (genetics)</term><term>Tumor Suppressor Proteins (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Agénésie du corps calleux (génétique)</term><term>Cellules souches neurales (anatomopathologie)</term><term>Corps calleux (anatomopathologie)</term><term>Encéphale (anatomopathologie)</term><term>Famille</term><term>Femelle</term><term>Humains</term><term>Incapacités de développement (génétique)</term><term>Malformations du système nerveux (génétique)</term><term>Malformations multiples (génétique)</term><term>Mutation (génétique)</term><term>Mâle</term><term>Phénotype</term><term>Protéines suppresseurs de tumeurs (génétique)</term><term>Pénétrance</term><term>Récepteurs de surface cellulaire (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Receptors, Cell Surface</term><term>Tumor Suppressor Proteins</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Cellules souches neurales</term><term>Corps calleux</term><term>Encéphale</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Abnormalities, Multiple</term><term>Agenesis of Corpus Callosum</term><term>Developmental Disabilities</term><term>Mutation</term><term>Nervous System Malformations</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Agénésie du corps calleux</term><term>Incapacités de développement</term><term>Malformations du système nerveux</term><term>Malformations multiples</term><term>Mutation</term><term>Protéines suppresseurs de tumeurs</term><term>Récepteurs de surface cellulaire</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term><term>Corpus Callosum</term><term>Neural Stem Cells</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Family</term><term>Female</term><term>Humans</term><term>Male</term><term>Penetrance</term><term>Phenotype</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Famille</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Phénotype</term><term>Pénétrance</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Brain malformations involving the corpus callosum are common in children with developmental disabilities. We identified DCC mutations in four families and five sporadic individuals with isolated agenesis of the corpus callosum (ACC) without intellectual disability. DCC mutations result in variable dominant phenotypes with decreased penetrance, including mirror movements and ACC associated with a favorable developmental prognosis. Possible phenotypic modifiers include the type and location of mutation and the sex of the individual.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Canada</li><li>France</li><li>États-Unis</li></country><region><li>Alsace (région administrative)</li><li>Californie</li><li>Grand Est</li><li>Québec</li><li>Région Bretagne</li><li>Victoria (État)</li><li>Île-de-France</li></region><settlement><li>Melbourne</li><li>Montréal</li><li>Paris</li><li>Rennes</li><li>Strasbourg</li></settlement><orgName><li>Université McGill</li><li>Université de Melbourne</li><li>Université de Strasbourg</li></orgName></list><tree><country name="Australie"><noRegion><name sortKey="Marsh, Ashley P L" sort="Marsh, Ashley P L" uniqKey="Marsh A" first="Ashley P L" last="Marsh">Ashley P L. Marsh</name></noRegion><name sortKey="Amor, David J" sort="Amor, David J" uniqKey="Amor D" first="David J" last="Amor">David J. Amor</name><name sortKey="Anderson, Vicki" sort="Anderson, Vicki" uniqKey="Anderson V" first="Vicki" last="Anderson">Vicki Anderson</name><name sortKey="Bahlo, Melanie" sort="Bahlo, Melanie" uniqKey="Bahlo M" first="Melanie" last="Bahlo">Melanie Bahlo</name><name sortKey="Bunt, Jens" sort="Bunt, Jens" uniqKey="Bunt J" first="Jens" last="Bunt">Jens Bunt</name><name sortKey="Delatycki, Martin B" sort="Delatycki, Martin B" uniqKey="Delatycki M" first="Martin B" last="Delatycki">Martin B. Delatycki</name><name sortKey="Edwards, Timothy J" sort="Edwards, Timothy J" uniqKey="Edwards T" first="Timothy J" last="Edwards">Timothy J. Edwards</name><name sortKey="Galea, Charles" sort="Galea, Charles" uniqKey="Galea C" first="Charles" last="Galea">Charles Galea</name><name sortKey="Gillies, Greta" sort="Gillies, Greta" uniqKey="Gillies G" first="Greta" last="Gillies">Greta Gillies</name><name sortKey="Gobius, Ilan" sort="Gobius, Ilan" uniqKey="Gobius I" first="Ilan" last="Gobius">Ilan Gobius</name><name sortKey="Leventer, Richard J" sort="Leventer, Richard J" uniqKey="Leventer R" first="Richard J" last="Leventer">Richard J. Leventer</name><name sortKey="Lockhart, Paul J" sort="Lockhart, Paul J" uniqKey="Lockhart P" first="Paul J" last="Lockhart">Paul J. Lockhart</name><name sortKey="Lukic, Vesna" sort="Lukic, Vesna" uniqKey="Lukic V" first="Vesna" last="Lukic">Vesna Lukic</name><name sortKey="Mandelstam, Simone A" sort="Mandelstam, Simone A" uniqKey="Mandelstam S" first="Simone A" last="Mandelstam">Simone A. 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Robinson</name><name sortKey="Spencer Smith, Megan" sort="Spencer Smith, Megan" uniqKey="Spencer Smith M" first="Megan" last="Spencer-Smith">Megan Spencer-Smith</name><name sortKey="Stephenson, Sarah E M" sort="Stephenson, Sarah E M" uniqKey="Stephenson S" first="Sarah E M" last="Stephenson">Sarah E M. Stephenson</name><name sortKey="Tankard, Rick" sort="Tankard, Rick" uniqKey="Tankard R" first="Rick" last="Tankard">Rick Tankard</name><name sortKey="Wood, Amanda" sort="Wood, Amanda" uniqKey="Wood A" first="Amanda" last="Wood">Amanda Wood</name></country><country name="France"><region name="Île-de-France"><name sortKey="Heron, Delphine" sort="Heron, Delphine" uniqKey="Heron D" first="Delphine" last="Heron">Delphine Heron</name></region><name sortKey="Attie Bitach, Tania" sort="Attie Bitach, Tania" uniqKey="Attie Bitach T" first="Tania" last="Attié-Bitach">Tania Attié-Bitach</name><name sortKey="Billette De Villemeur, Thierry" sort="Billette De Villemeur, Thierry" uniqKey="Billette De Villemeur T" first="Thierry" last="Billette De Villemeur">Thierry Billette De Villemeur</name><name sortKey="Bitoun, Pierre" sort="Bitoun, Pierre" uniqKey="Bitoun P" first="Pierre" last="Bitoun">Pierre Bitoun</name><name sortKey="Brice, Alexis" sort="Brice, Alexis" uniqKey="Brice A" first="Alexis" last="Brice">Alexis Brice</name><name sortKey="Depienne, Christel" sort="Depienne, Christel" uniqKey="Depienne C" first="Christel" last="Depienne">Christel Depienne</name><name sortKey="Faudet, Anne" sort="Faudet, Anne" uniqKey="Faudet A" first="Anne" last="Faudet">Anne Faudet</name><name sortKey="Garel, Catherine" sort="Garel, Catherine" uniqKey="Garel C" first="Catherine" last="Garel">Catherine Garel</name><name sortKey="Guegan, Justine" sort="Guegan, Justine" uniqKey="Guegan J" first="Justine" last="Guegan">Justine Guegan</name><name sortKey="Heide, Solveig" sort="Heide, Solveig" uniqKey="Heide S" first="Solveig" last="Heide">Solveig Heide</name><name sortKey="Keren, Boris" sort="Keren, Boris" uniqKey="Keren B" first="Boris" last="Keren">Boris Keren</name><name sortKey="Lesne, Fabien" sort="Lesne, Fabien" uniqKey="Lesne F" first="Fabien" last="Lesne">Fabien Lesne</name><name sortKey="Mandel, Jean Louis" sort="Mandel, Jean Louis" uniqKey="Mandel J" first="Jean-Louis" last="Mandel">Jean-Louis Mandel</name><name sortKey="Meneret, Aurelie" sort="Meneret, Aurelie" uniqKey="Meneret A" first="Aurélie" last="Méneret">Aurélie Méneret</name><name sortKey="Mignot, Cyril" sort="Mignot, Cyril" uniqKey="Mignot C" first="Cyril" last="Mignot">Cyril Mignot</name><name sortKey="Moutard, Marie Laure" sort="Moutard, Marie Laure" uniqKey="Moutard M" first="Marie-Laure" last="Moutard">Marie-Laure Moutard</name><name sortKey="Nava, Caroline" sort="Nava, Caroline" uniqKey="Nava C" first="Caroline" last="Nava">Caroline Nava</name><name sortKey="Odent, Sylvie" sort="Odent, Sylvie" uniqKey="Odent S" first="Sylvie" last="Odent">Sylvie Odent</name><name sortKey="Piton, Amelie" sort="Piton, Amelie" uniqKey="Piton A" first="Amélie" last="Piton">Amélie Piton</name><name sortKey="Quartier, Angelique" sort="Quartier, Angelique" uniqKey="Quartier A" first="Angélique" last="Quartier">Angélique Quartier</name><name sortKey="Rastetter, Agnes" sort="Rastetter, Agnes" uniqKey="Rastetter A" first="Agnès" last="Rastetter">Agnès Rastetter</name><name sortKey="Riant, Florence" sort="Riant, Florence" uniqKey="Riant F" first="Florence" last="Riant">Florence Riant</name><name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name><name sortKey="Trouillard, Oriane" sort="Trouillard, Oriane" uniqKey="Trouillard O" first="Oriane" last="Trouillard">Oriane Trouillard</name><name sortKey="Welniarz, Quentin" sort="Welniarz, Quentin" uniqKey="Welniarz Q" first="Quentin" last="Welniarz">Quentin Welniarz</name></country><country name="Canada"><region name="Québec"><name sortKey="Srour, Myriam" sort="Srour, Myriam" uniqKey="Srour M" first="Myriam" last="Srour">Myriam Srour</name></region><name sortKey="Rouleau, Guy" sort="Rouleau, Guy" uniqKey="Rouleau G" first="Guy" last="Rouleau">Guy Rouleau</name></country><country name="États-Unis"><region name="Californie"><name sortKey="Sherr, Elliott H" sort="Sherr, Elliott H" uniqKey="Sherr E" first="Elliott H" last="Sherr">Elliott H. 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